DOLPP1 Antibody

CATALOG NUMBER: 57-181

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This DOLPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the C-terminal region of human DOLPP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
27 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DOLPP1
Additional Names:
Dolichyldiphosphatase 1, Dolichyl pyrophosphate phosphatase 1, DOLPP1, LSFR2
Protein Accession Number:
Q86YN1
Protein Gi Number:
45476905
Ncbi Gene Id Number:
57171
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
DOLPP1 is required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity).
Background Reference 1:
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Background Reference 2:
Rush, J.S., et al. J. Biol. Chem. 277(47):45226-45234(2002)
Background Reference 3:
Gilley, J., et al. Hum. Mol. Genet. 8(7):1313-1320(1999)
Background Reference 4:
Wedgwood, J.F., et al. J. Biol. Chem. 255(3):1120-1123(1980)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-181

List Size:
400 ul

List Price:

$495.00

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