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Western blot analysis in Jurkat,K562 cell line lysates (35ug/lane).
DPYS Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in Jurkat,K562 cell line lysates (35ug/lane).

DPYS Antibody

CATALOG NUMBER: 57-041

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DPYS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human DPYS.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
57 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DPYS
Additional Names:
Dihydropyrimidinase, DHP, DHPase, Dihydropyrimidine amidohydrolase, Hydantoinase, DPYS
Protein Accession Number:
Q14117
Protein Gi Number:
3122049
Ncbi Gene Id Number:
1807
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Dihydropyrimidinase catalyzes the conversion of5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism.Dihydropyrimidinase is expressed at a high level in liver andkidney as a major 2.5-kb transcript and a minor 3.8-kb transcript.Defects in the DPYS gene are linked to dihydropyrimidinuria.
Background Reference 1:
Kim, H.Y., et al. BMB Rep 43(8):547-553(2010)
Background Reference 2:
van Kuilenburg, A.B., et al. Biochim. Biophys. Acta 1802 (7-8), 639-648 (2010) :
Background Reference 3:
Fidlerova, J., et al. Cancer Chemother. Pharmacol. 65(4):661-669(2010)
Background Reference 4:
Thomas, H.R., et al. Pharmacogenet. Genomics 18(1):25-35(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-041

List Size:
400 ul

List Price:

$495.00

Datasheet
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