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DR6 Recombinant Protein

CATALOG NUMBER: 90-226

Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).
Fusion Tag:
Fc Tag
Application Note:
This recombinant proteins is for research use only.
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
physical-state:
Lyophilized
Buffer:
Contains PBS. Reconstitute with 50 μl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
Concentration:
1mg/ml after reconstitution.
Storage Conditions:
Stable for at least 6 months after receipt when stored at -20°C.
Ncbi Official Symbol:
TNFRSF21
Additional Names:
Tumor Necrosis Factor Receptor Superfamily Member 21, TNFRSF21, Death Receptor 6, CD358
Protein Accession Number:
O75509
Protein Gi Number:
3549262
Ncbi Gene Id Number:
27242
Background:
DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-226

List Size:
50 ug

List Price:

$365.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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