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Western blot testing of human samples using DRAM antibody at 4ug/ml.
Western blot testing of human samples using DRAM antibody at 4ug/ml.

DRAM Antibody

CATALOG NUMBER: 33-062

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
A recombinant protein fragment from the N-terminal region of human DRAM was used as the immunogen for this antibody.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western blot: 4-8 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Purification:
Protein A affinity chromatography
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Storage Conditions:
Aliquot and Store at -20°C. Avoid freez-thaw cycles.
Ncbi Official Symbol:
DRAM
Additional Names:
DRAM Antibody: DRAM, DRAM, DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator
Ncbi Gene Id Number:
55332
User Note:
Optimal dilutions for each application to be determined by the researcher
Background:
Autophagy is the mechanism by which lysosomes degrade unneeded or dysfunctional cellular components. p53 is a tumor suppressor protein that modulates autophagy and apoptosis. DRAM, or damage regulated autophagy modulator, is a lysosomal protein and effector of p53-mediated cell death. Many tumors show decreased DRAM expression and siRNA knockdown resulted in reduced cell death (Crighton et al, 2006).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

33-062

List Size:
100 ug

List Price:

$520.00

Datasheet
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