DRD2 Antibody

CATALOG NUMBER: 58-687

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This DRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human DRD2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
51 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DRD2
Additional Names:
D(2) dopamine receptor, Dopamine D2 receptor, DRD2
Protein Accession Number:
P14416
Protein Gi Number:
118206
Ncbi Gene Id Number:
1813
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the D2 subtype of the dopamine receptor.This G-protein coupled receptor inhibits adenylyl cyclase activity.A missense mutation in this gene causes myoclonus dystonia; othermutations have been associated with schizophrenia. Alternativesplicing of this gene results in two transcript variants encodingdifferent isoforms. A third variant has been described, but it hasnot been determined whether this form is normal or due to aberrantsplicing.
Background Reference 1:
Verma, V., et al. J. Biol. Chem. 285(45):35092-35103(2010)
Background Reference 2:
Borroto-Escuela, D.O., et al. Biochem. Biophys. Res. Commun. 401(4):605-610(2010)
Background Reference 3:
Stelzel, C., et al. J. Neurosci. 30(42):14205-14212(2010)
Background Reference 4:
Huang, H.Y., et al. J. Formos. Med. Assoc. 109(10):736-739(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-687

List Size:
400 ul

List Price:

$495.00

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