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Antibody is used in Western blot to detect Drosophila Parkin in, from left to right, mouse kidney, mouse brain, mouse heart, Ramos, and Hela tissue lysates.
Antibody is used in Western blot to detect Drosophila Parkin in, from left to right, mouse kidney, mouse brain, mouse heart, Ramos, and Hela tissue lysates.

Drosophila Parkin Antibody

CATALOG NUMBER: 62-278

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Drosophila
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Drosophila
Immunogen:
This Drosophila Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the N-terminal region of human Drosophila Parkin.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
54 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Q7KTX7
Additional Names:
CG10523-PB; isoform B; Cg10523-pc; isoform c; PARKIN; park; parkin;
Protein Accession Number:
Q7KTX7
Ncbi Gene Id Number:
40336
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Parkin is thought to play a role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. Mutations in the human version of the protein are known to cause autosomal recessive juvenile parkinsonism.
Background Reference 1:
Zhong,L. et al. J. Biol. Chem. 280 (10), 9425-9430 (2005)
Background Reference 2:
Pesah,Y. et al. Development 131 (9), 2183-2194 (2004)
Background Reference 3:
Haywood,A.F. et al. BMC Neurosci 5, 14 (2004)
Background Reference 4:
Finney,N. et al. J. Biol. Chem. 278 (18), 16054-16058 (2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-278

List Size:
400 ul

List Price:

$495.00

Datasheet
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