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Western blot analysis of extracts from JK cells and K562 cells using DRP1 (Phospho-Ser637) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from JK cells and K562 cells using DRP1 (Phospho-Ser637) Antibody. The lane on the right is treated with the antigen-specific peptide.

DRP1 (phospho Ser637) Antibody

CATALOG NUMBER: 79-951

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
DRP1 (phospho Ser637) antibody was raised against a peptide sequence around phosphorylation site of Serine 637 (K-L-S (p)-A-R) derived from Human DRP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637.
Predicted Molecular Weight:
82 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
DNM1L
Additional Names:
DLP1, DNM1L, DRP1, DVLP, Dymple
Protein Accession Number:
NP_036192.2
Protein Gi Number:
171460914
Ncbi Gene Id Number:
10059
Background:
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation.
Background Reference 1:
Shin H.-W., J. Biochem. 122:525-530(1997).
Background Reference 2:
Hong Y.-R., Biochem. Biophys. Res. Commun. 249:697-703(1998).
Background Reference 3:
Imoto M., J. Cell Sci. 111:1341-1349(1998).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-951

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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