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Western blot analysis of lysate from A431 cell line, using DSC3 Antibody at 1:1000 at each lane.
Western blot analysis of lysate from A431 cell line, using DSC3 Antibody at 1:1000 at each lane.

DSC3 Antibody

CATALOG NUMBER: 58-711

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DSC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of human DSC3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
100 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DSC3
Additional Names:
Desmocollin-3, Cadherin family member 3, Desmocollin-4, HT-CP, DSC3, CDHF3, DSC4
Protein Accession Number:
Q14574
Protein Gi Number:
116241342
Ncbi Gene Id Number:
1825
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a calcium-dependentglycoprotein that is a member of the desmocollin subfamily of thecadherin superfamily. These desmosomal family members, along withthe desmogleins, are found primarily in epithelial cells where theyconstitute the adhesive proteins of the desmosome cell-celljunction and are required for cell adhesion and desmosomeformation. The desmosomal family members are arranged in twoclusters on chromosome 18, occupying less than 650 kb combined.Alternative splicing results in two transcript variants encodingdistinct isoforms.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Background Reference 3:
Spindler, V., et al. J. Biol. Chem. 284(44):30556-30564(2009)
Background Reference 4:
Ayub, M., et al. Am. J. Hum. Genet. 85(4):515-520(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-711

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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