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Western blot analysis in 293 cell line lysates (35ug/lane).
DSG2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in 293 cell line lysates (35ug/lane).

DSG2 Antibody

CATALOG NUMBER: 57-710

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 829-857 amino acids from the C-terminal region of human DSG2.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
122 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DSG2
Additional Names:
Desmoglein-2, Cadherin family member 5, HDGC, DSG2, CDHF5
Protein Accession Number:
Q14126
Protein Gi Number:
148876773
Ncbi Gene Id Number:
1829
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Desmosomes are cell-cell junctions between epithelial,myocardial, and certain other cell types. This gene product is acalcium-binding transmembrane glycoprotein component of desmosomesin vertebrate epithelial cells. Currently, three desmogleinsubfamily members have been identified and all are members of thecadherin cell adhesion molecule superfamily. These desmoglein genefamily members are located in a cluster on chromosome 18. Thissecond family member is expressed in colon, colon carcinoma, andother simple and stratified epithelial-derived cell lines.Mutations in this gene have been associated with arrhythmogenicright ventricular dysplasia, familial, 10.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Fressart, V., et al. Europace 12(6):861-868(2010)
Background Reference 3:
Schlegel, N., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (5), G774-G783 (2010) :
Background Reference 4:
Cox, M.G., et al. Circ Arrhythm Electrophysiol 3(2):126-133(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-710

List Size:
400 ul

List Price:

$495.00

Datasheet
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