DTNA Antibody

CATALOG NUMBER: 56-512

Clonality:
Polyclonal
Tested Applications:
IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This DTNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human DTNA.
Conjugate:
Unconjugated
Tested Applications:
IF, IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Predicted Molecular Weight:
84 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DTNA
Additional Names:
Dystrobrevin alpha, DTN-A, Alpha-dystrobrevin, Dystrophin-related protein 3, DTNA, DRP3
Protein Accession Number:
Q9Y4J8
Protein Gi Number:
229462840
Ncbi Gene Id Number:
1837
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to thedystrobrevin subfamily of the dystrophin family. This protein is acomponent of the dystrophin-associated protein complex (DPC), whichconsists of dystrophin and several integral and peripheral membraneproteins, including dystroglycans, sarcoglycans, syntrophins andalpha- and beta-dystrobrevin. The DPC localizes to the sarcolemmaand its disruption is associated with various forms of musculardystrophy. Mutations in this gene are associated with leftventricular noncompaction with congenital heart defects. Multiplealternatively spliced transcript variants encoding differentisoforms have been identified for this gene.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Bohm, S.V., et al. BMC Biol. 7, 85 (2009) :
Background Reference 3:
Nakamori, M., et al. Neurology 70(9):677-685(2008)
Background Reference 4:
Lamesch, P., et al. Genomics 89(3):307-315(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-512

List Size:
400 ul

List Price:

$495.00

Shipping Info
Customize your order
Custom Antibody Services

New & Featured Products

CATALOG NUMBER: PM-7369-HRP

CATALOG NUMBER: PM-7369-biotin

CATALOG NUMBER: PM-7369