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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

DUS2L Antibody

CATALOG NUMBER: 59-760

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DUS2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the C-terminal region of human DUS2L.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DUS2
Additional Names:
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, 131-, Dihydrouridine synthase 2, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2, DUS2, DUS2L
Protein Accession Number:
Q9NX74
Protein Gi Number:
73620832
Ncbi Gene Id Number:
54920
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Dihydrouridine synthase catalyzes reduction of the5,6-double bond of a uridine residue on the displacement loop oftRNA. The resultant modified base, 5,6-dihydrouridine, appears toincrease the conformational flexibility and dynamic motion of tRNA(Kato et al., 2005 [PubMed 15994936]).
Background Reference 1:
Mittelstadt, M., et al. Nucleic Acids Res. 36(3):998-1008(2008)
Background Reference 2:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Background Reference 3:
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Background Reference 4:
Kato, T., et al. Cancer Res. 65(13):5638-5646(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-760

List Size:
400 ul

List Price:

$495.00

Datasheet
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