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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

DUSP14 Antibody

CATALOG NUMBER: 60-909

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This DUSP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human DUSP14.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
22 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DUSP14
Additional Names:
Dual specificity protein phosphatase 14, MKP-1-like protein tyrosine phosphatase, MKP-L, Mitogen-activated protein kinase phosphatase 6, MAP kinase phosphatase 6, MKP-6, DUSP14, MKP6
Protein Accession Number:
O95147
Ncbi Gene Id Number:
11072
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Dual-specificity phosphatases (DUSPs) constitute a largeheterogeneous subgroup of the type I cysteine-basedprotein-tyrosine phosphatase superfamily. DUSPs are characterizedby their ability to dephosphorylate both tyrosine andserine/threonine residues. They have been implicated as majormodulators of critical signaling pathways. DUSP14 contains theconsensus DUSP C-terminal catalytic domain but lacks the N-terminalCH2 domain found in the MKP (mitogen-activated protein kinasephosphatase) class of DUSPs (see MIM 600714) (summary by Pattersonet al., 2009 [PubMed 19228121]).
Background Reference 1:
Thye, T., et al. Nat. Genet. 42(9):739-741(2010)
Background Reference 2:
Lountos, G.T., et al. Acta Crystallogr.Biol. Crystallogr. 65 (PT 10), 1013-1020 (2009) :
Background Reference 3:
Patterson, K.I., et al. Biochem. J. 418(3):475-489(2009)
Background Reference 4:
Elass, E., et al. FEBS Lett. 582(3):445-450(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-909

List Size:
400 ul

List Price:

$469.00

Out of stock

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