DUSP6 Antibody

CATALOG NUMBER: XW-7838

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
135-280
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Dual specificity phosphatase 6 antibody can be used for the detection of Dual specificity phosphatase 6 by Western Blot.
Predicted Molecular Weight:
15.1 kDa (calculated)
Purification:
Immunoaffinity Purified
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
DUSP6 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DUSP6
Additional Names:
MKP3, PYST1, Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, MAP kinase phosphatase 3, HH19, MKP3, Dual specificity phosphatase 6
Protein Accession Number:
NP_001937.1
Protein Gi Number:
4503419
Ncbi Gene Id Number:
1848
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This protein product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7838

List Size:
0.05 mg

List Price:

$638.00

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