DVL2 Antibody

CATALOG NUMBER: 58-081

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This DVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the C-terminal region of human DVL2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
79 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DVL2
Additional Names:
Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2, DVL2
Protein Accession Number:
O14641
Ncbi Gene Id Number:
1856
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the dishevelled (dsh)protein family. The vertebrate dsh proteins have approximately 40%amino acid sequence similarity with Drosophila dsh. This geneencodes a 90-kD protein that undergoes posttranslationalphosphorylation to form a 95-kD cytoplasmic protein, which may playa role in the signal transduction pathway mediated by multiple Wntproteins. The mechanisms of dishevelled function in Wnt signalingare likely to be conserved among metazoans.
Background Reference 1:
Inkster, B., et al. Neuroimage 53(3):908-917(2010)
Background Reference 2:
Kikuchi, K., et al. EMBO J. 29(20):3470-3483(2010)
Background Reference 3:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 4:
Gao, C., et al. Nat. Cell Biol. 12(8):781-790(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-081

List Size:
400 ul

List Price:

$495.00

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