Ebselen

CATALOG NUMBER: 10-023

Specifications

Predicted Molecular Weight:

274.2

Formula:

C13H9NOSe

Cas:

60940-34-3

Solubility:

Soluble in DMSO (25mg/ml), DMF (25mg/ml) or water (2mg/ml).

Inchi Key:

DYEFUKCXAQOFHX-UHFFFAOYSA-N

Smiles:

O=C1N([Se]C2=C1C=CC=C2)C1=CC=CC=C1

Identity:

Determined by 1H-NMR.

Merck Index:

3.004166667

Advanced Validation

Properties

Purity:

greater than or equal to 98% (HPLC)

physical-state:

Lyophilized

Storage Conditions:

Short Term Storage:+4C. Long Term Storage: -20C. Handling Advice: Protect from light. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.

Additional Info

Additional Names:

2-Phenyl-1,2-benzisoselenazol-3-(2H)-one

Background

Background:

Glutathione peroxidase mimetic [1, 4]. Peroxynitrite scavenger [4]. Anti-inflammatory [1, 5-7] Antioxidant [2, 3, 5]. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor [6-9]. Antifungal [9]. Review [10]. Potent IDO-1 inhibitor with Ki 94nM [11]. Inhibitor of HIV-1 capsid C-terminal domain dimerization. Shown to potentially inhibit the 33.8-kDa Main Protease (Mpro)/3C-like Protease of SARS-CoV-2, consequently inhibiting viral transcription and replication and possibly inhibiting spread of COVID-19

Citations

Set Contents

Disclaimer

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:

This product is for research use only.

CATALOG NUMBER:

10-023

List Size:

25 mg

List Price:

$215.00

Datasheet

Shipping Info

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