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Western blot analysis in A2058 cell line lysates (35ug/lane).
Western blot analysis in A2058 cell line lysates (35ug/lane).

EDEM3 Antibody

CATALOG NUMBER: 58-568

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This EDEM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-802 amino acids from the C-terminal region of human EDEM3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
105 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
EDEM3
Additional Names:
ER degradation-enhancing alpha-mannosidase-like protein 3, Alpha-1,2-mannosidase EDEM3, EDEM3, C1orf22
Protein Accession Number:
Q9BZQ6
Protein Gi Number:
166897965
Ncbi Gene Id Number:
80267
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Quality control in the endoplasmic reticulum (ER) ensuresthat only properly folded proteins are retained in the cell throughrecognition and degradation of misfolded or unassembled proteins.EDEM3 belongs to a group of proteins that accelerate degradation ofmisfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed16431915]).
Background Reference 1:
Hirao, K., et al. J. Biol. Chem. 281(14):9650-9658(2006)
Background Reference 2:
Mast, S.W., et al. Glycobiology 15(4):421-436(2005)
Background Reference 3:
Olivari, S., et al. J. Biol. Chem. 280(4):2424-2428(2005)
Background Reference 4:
Sood, R., et al. Genomics 73(2):211-222(2001)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-568

List Size:
400 ul

List Price:

$495.00

Datasheet
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