EIF2S2 Antibody

CATALOG NUMBER: 60-960

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit
Immunogen:
This EIF2S2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the C-terminal region of human EIF2S2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
38 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
EIF2S2
Additional Names:
Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit beta, eIF-2-beta, EIF2S2, EIF2B
Protein Accession Number:
P20042
Protein Gi Number:
12644154
Ncbi Gene Id Number:
8894
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Eukaryotic translation initiation factor 2 (EIF-2)functions in the early steps of protein synthesis by forming aternary complex with GTP and initiator tRNA and binding to a 40Sribosomal subunit. EIF-2 is composed of three subunits, alpha,beta, and gamma, with the protein encoded by this gene representingthe beta subunit. The beta subunit catalyzes the exchange of GDPfor GTP, which recycles the EIF-2 complex for another round ofinitiation.
Background Reference 1:
Rajesh, K., et al. Biochem. Biophys. Res. Commun. 374(2):336-340(2008)
Background Reference 2:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Background Reference 3:
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Background Reference 4:
Olsen, J.V., et al. Cell 127(3):635-648(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-960

List Size:
400 ul

List Price:

$495.00

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