EIF4EBP2 Antibody

CATALOG NUMBER: 60-797

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This EIF4EBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human EIF4EBP2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
13 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
EIF4EBP2
Additional Names:
Eukaryotic translation initiation factor 4E-binding protein 2, 4E-BP2, eIF4E-binding protein 2, EIF4EBP2
Protein Accession Number:
Q13542
Protein Gi Number:
34921510
Ncbi Gene Id Number:
1979
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the eukaryotic translationinitiation factor 4E binding protein family. The gene products ofthis family bind eIF4E and inhibit translation initiation. However,insulin and other growth factors can release this inhibition via aphosphorylation-dependent disruption of their binding to eIF4E.Regulation of protein production through these gene products havebeen implicated in cell proliferation, cell differentiation andviral infection.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Bidinosti, M., et al. J. Biol. Chem. 285(25):19402-19408(2010)
Background Reference 3:
Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-797

List Size:
400 ul

List Price:

$495.00

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