EIF4EBP2 Antibody

CATALOG NUMBER: XW-7175

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
1-120
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
EIF4EBP2 antibody can be used for the detection of EIF4EBP2 by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
12.9 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
EIF4EBP2 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
EIF4EBP2
Additional Names:
Eukaryotic translation initiation factor 4E-binding protein 24E-BP2, 4EBP2, PHASII,
Protein Accession Number:
NP_004087.1
Protein Gi Number:
4758260
Ncbi Gene Id Number:
1979
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Eukaryotic translation initiation factor 4E binding protein 2; Eukaryotic translation initiation factor-4E binding protein-1. This protein regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. Nonphosphorylated EIF4EBP2 interacts with EIF4E. Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF. Belongs to the eIF4E binding protein family.
Background Reference 1:
Dilling,M. B., Germain,G. S., Dudkin,L., Jayaraman,A. L., Zhang,X., Harwood,F. C. and Houghton,P. J. 4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin. J. Biol. Chem. 277 (16), 13907-13917 (2002).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7175

List Size:
0.05 mg

List Price:

$565.00

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