ELAVL3 Antibody

CATALOG NUMBER: 56-996

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ELAVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human ELAVL3.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
40 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ELAVL3
Additional Names:
ELAV-like protein 3, Hu-antigen C, HuC, Paraneoplastic cerebellar degeneration-associated antigen, Paraneoplastic limbic encephalitis antigen 21, ELAVL3, HUC, PLE21
Protein Accession Number:
Q14576
Protein Gi Number:
21264436
Ncbi Gene Id Number:
1995
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
A member of the ELAVL protein family, ELAV-like 3 is aneural-specific RNA-binding protein which contains three RNP-typeRNA recognition motifs. The observation that ELAVL3 is one ofseveral Hu antigens (neuronal-specific RNA-binding proteins)recognized by the anti-Hu serum antibody present in sera frompatients with paraneoplastic encephalomyelitis and sensoryneuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Twoalternatively spliced transcript variants encoding distinctisoforms have been found for this gene.
Background Reference 1:
Behrends, U., et al. Int. J. Cancer 100(6):669-677(2002)
Background Reference 2:
Park, S., et al. Mol. Cell. Biol. 20(13):4765-4772(2000)
Background Reference 3:
King, P.H. Nucleic Acids Res. 28 (7), E20 (2000) :
Background Reference 4:
Sakai, K., et al. Biochem. Biophys. Res. Commun. 256(2):263-268(1999)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-996

List Size:
400 ul

List Price:

$495.00

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