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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Elk-1 (Ab-383).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Elk-1 (Ab-383).

Elk 1 (Ab 383) Antibody

CATALOG NUMBER: 79-255

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Elk-1 (Ab-383) antibody was raised against a peptide sequence around aa.381~385 (T-L-S-P-I) derived from Human Elk1.
Conjugate:
Unconjugated
Tested Applications:
IHC
Application Note:
Immunohistochemistry: 1:50~1:100
Specificity:
This antibody detects endogenous level of total Elk-1 protein.
Predicted Molecular Weight:
47 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ELK1
Additional Names:
Mek5, Mkk5, Prkmk5, ELK1, ETS-domain protein Elk-1
Protein Accession Number:
NP_001107595.1
Protein Gi Number:
166362732
Ncbi Gene Id Number:
2002
Background:
Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene
Background Reference 1:
Xing J, et al. (1996) Science. 273 (5277): 959-963. Janknecht R, et al. (1993) EMBO J. 12 (13): 5097-5104. Marais R, et al. (1993) Cell 73: 381-393. Kortenjann M, et al. (1994) Mol Cell Biol. 14: 4815-4824. Cavigelli M, et al. (1995) EMBO J. 14: 5957-5964. Whitmarsh A J, et al. (1995) Science. 269:403-407.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-255

List Size:
0.1 mg

List Price:

$370.00

Datasheet
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