ELK3 Antibody

CATALOG NUMBER: 58-514

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ELK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human ELK3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ELK3
Additional Names:
ETS domain-containing protein Elk-3, ETS-related protein ERP, ETS-related protein NET, Serum response factor accessory protein 2, SAP-2, SRF accessory protein 2, ELK3, NET, SAP2
Protein Accession Number:
P41970
Protein Gi Number:
116241349
Ncbi Gene Id Number:
2004
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of theETS-domain transcription factor family and the ternary complexfactor (TCF) subfamily. Proteins in this subfamily regulatetranscription when recruited by serum response factor to bind toserum response elements. This protein is activated bysignal-induced phosphorylation; studies in rodents suggest that itis a transcriptional inhibitor in the absence of Ras, but activatestranscription when Ras is present.
Background Reference 1:
Serchov, T., et al. J. Biol. Chem. 285(28):21223-21232(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Li, B., et al. Tohoku J. Exp. Med. 216(2):139-147(2008)
Background Reference 4:
Wasylyk, C., et al. Cancer Res. 68(5):1275-1283(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-514

List Size:
400 ul

List Price:

$495.00

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