ENA-78 Recombinant Protein

CATALOG NUMBER: 40-373

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN
Biological Activity:
Biological activity was determined by its ability to chemoattract human peripheral blood neutrophils using a concentration of 5.0 - 10.0 ng/mL.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized ENA-78 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted ENA-78 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing ENA-78 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
CXCL5
Additional Names:
SCYB5, ENA-78, ENA78, SCYB5, C-X-C motif chemokine 5, Epithelial-derived neutrophil-activating protein 78
Protein Accession Number:
NP_002985.1
Protein Gi Number:
4506849
Ncbi Gene Id Number:
6374
Background:
ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokines that bind to the CXCR1 and CXCR2 receptors. Recombinant Human ENA-78 is an 8.0 kDa protein consisting of 74 amino acid residues.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-373

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $215.00 through $323.00

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