ENSA Antibody

CATALOG NUMBER: XW-7177

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
1-121
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
ENSA antibody can be used for the detection of ENSA by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
13.4 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
ENSA antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ENSA
Additional Names:
Alpha-endosulfine, ARPP-19e,
Protein Accession Number:
NP_004427.1
Protein Gi Number:
4758272
Ncbi Gene Id Number:
2029
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Endosulfine α. α-endosulfine is expressed in a wide range of tissues including muscle, brain, and endocrine tissues. The recombinant protein inhibits binding of labeled glibenclamide to β cell membranes. It also inhibits cloned K(ATP) channel currents and thereby stimulates insulin secretion. It was proposed that endosulfine is an endogenous regulator of the K(ATP) channel, which has a key role in the control of insulin release and, more generally, couples cell metabolism to electrical activity.
Background Reference 1:
Heron, L., Virsolvy, A., Peyrollier, K., Gribble, F. M., Le Cam, A., Ashcroft, F. M., Bataille, D. Human alpha-endosulfine, a possible regulator of sulfonylurea-sensitive K(ATP) channel: molecular cloning, expression and biological properties. Proc. Nat. Acad. Sci. 95: 8387-8391, 1998.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7177

List Size:
0.05 mg

List Price:

$565.00

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