EPB41 (phospho Tyr660/418) Antibody

CATALOG NUMBER: 79-909

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
EPB41 (phospho Tyr660/418) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y (p)-I-R)derived from Human EPB41.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of EPB41 only when phosphorylated at tyrosine 660/418.
Predicted Molecular Weight:
60 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
EPB41
Additional Names:
E41P, EPB4.1, band 4.1, P4.1
Protein Accession Number:
NP_001159477.1
Protein Gi Number:
260436831
Ncbi Gene Id Number:
2035
Background:
Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.
Background Reference 1:
Conboy J.G., Proc. Natl. Acad. Sci. U.S.A. 83:9512-9516(1986).
Background Reference 2:
Tang T.K., Adv. Exp. Med. Biol. 241:81-95(1988).
Background Reference 3:
Tang T.K., Proc. Natl. Acad. Sci. U.S.A. 85:3713-3717(1988).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-909

List Size:
0.1 mg

List Price:

$376.00

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