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The purity of Rhesus Macaque EpCAM was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of Rhesus Macaque EpCAM was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

EpCAM Recombinant Protein

CATALOG NUMBER: 96-270

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Rhesus monkey
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gln 24 - Lys 265
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
28.2 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
EPCAM
Additional Names:
EPCAM, TACSTD1, TROP1, CD326, DIAR5, EGP2, EGP314, EGP40, ESA, GA733-2, HNPCC8, HNPCC-8, KS1/4, KSA, M4S1, MIC18, MK1
Protein Accession Number:
NP_001035118.1
Ncbi Gene Id Number:
677680
Background:
EpCAM is also known as CO171A,; EGP; EGP40; GA7332; KSA; M4S; MIC18; MK1; TROP1; hEGP2, and is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas as 17-1A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (Ep-CAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy.Ep-CAM cross signaling with N-cadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (Ep-CAM) recently received increased attention as a prognostic factor in breast cancer.
Background Reference 1:
Linnenbach, et al., 1993, Mol Cell Biol 13 (3): 1507–15.
Background Reference 2:
Akita H, et al., 2011, Oncogene.
Background Reference 3:
Winter MJ, et al., 2007, Mol Cell Biochem. 302(1-2):19-26.
Background Reference 4:
Schmidt M, et al., 2011, Breast Cancer Res Treat. 125(3):637-46.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-270

List Size:
0.05 mg

List Price:

$577.00

Datasheet
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