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Human PROCR, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human PROCR, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

EPCR Recombinant Protein

CATALOG NUMBER: 96-636

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Ser 18 - Thr 209
Fusion Tag:
C-Fc Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
48.6 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
PROCR
Additional Names:
PROCR, EPCR, CD201, APC receptor, CCCA, CCD41
Protein Accession Number:
AAH14451
Ncbi Gene Id Number:
10544
Background:
Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.
Background Reference 1:
Fukudome K., et al., 1994, J. Biol. Chem. 269:26486-26491.
Background Reference 2:
Oganesyan V., et al., 2002, J. Biol. Chem. 277:24851-24854.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-636

List Size:
0.1 mg

List Price:

$515.00

Datasheet
Shipping Info

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