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Western blot analysis of extracts from JK cells (Lane 2), using EPHA7 (Phospho-Tyr791) Antibody. The lane on the left is treated with antigen-specific peptide.
Western blot analysis of extracts from JK cells (Lane 2), using EPHA7 (Phospho-Tyr791) Antibody. The lane on the left is treated with antigen-specific peptide.

EPHA7 (phospho Tyr791) Antibody

CATALOG NUMBER: 79-944

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
EPHA7 (phospho Tyr791) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y (p)-T-T) derived from Human EPHA7 .
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of EPHA7only when phosphorylated at tyrosine 791.
Predicted Molecular Weight:
112 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
EPHA7
Additional Names:
EHK3, EK11, HEK11
Protein Accession Number:
NP_004431.1
Protein Gi Number:
146345416
Ncbi Gene Id Number:
2045
Background:
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.
Background Reference 1:
Fox G.M., Oncogene 10:897-905(1995).
Background Reference 2:
Mungall A.J., Nature 425:805-811(2003).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-944

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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