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Western blot analysis of extracts from K562 tissue using Epo-R (Phospho-Tyr368) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from K562 tissue using Epo-R (Phospho-Tyr368) Antibody. The lane on the right is treated with the antigen-specific peptide.

Epo-R (phospho Tyr368) Antibody

CATALOG NUMBER: 80-044

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Epo-R (phospho Tyr368) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y (p)-L-V) derived from Human Epo-R.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of Epo-R only when phosphorylated at tyrosine 368.
Predicted Molecular Weight:
55 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
EPOR
Additional Names:
EPO R, EPO-R, epor
Protein Accession Number:
NP_000112.1
Protein Gi Number:
4503591
Ncbi Gene Id Number:
2057
Background:
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
Background Reference 1:
Funakoshi-Tago M, et al. (2010) J Biol Chem 285, 5296-307
Background Reference 2:
Sulahian R, Cleaver O, Huang LJ (2009) Blood 113, 5287-97
Background Reference 3:
Zhang YL, et al. (2009) Mol Cell 33, 266-74

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

80-044

List Size:
0.1 mg

List Price:

$355.00

Out of stock

Datasheet
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