ERCC5 Antibody

CATALOG NUMBER: 59-501

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ERCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1151-1178 amino acids from the C-terminal region of human ERCC5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
133 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ERCC5
Additional Names:
DNA repair protein complementing XP-G cells, 31--, DNA excision repair protein ERCC-5, Xeroderma pigmentosum group G-complementing protein, ERCC5, ERCM2, XPG, XPGC
Protein Accession Number:
P28715
Protein Gi Number:
205371791
Ncbi Gene Id Number:
2073
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Excision repair cross-complementing rodent repairdeficiency, complementation group 5 (xeroderma pigmentosum,complementation group G) is involved in excision repair ofUV-induced DNA damage. Mutations cause Cockayne syndrome, which ischaracterized by severe growth defects, mental retardation, andcachexia. Multiple alternatively spliced transcript variantsencoding distinct isoforms have been described, but the biologicalvalidity of all variants has not been determined. [provided byRefSeq].
Background Reference 1:
Figl, A., et al. Mutat. Res. 702(1):8-16(2010)
Background Reference 2:
Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
Background Reference 3:
Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
Background Reference 4:
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-501

List Size:
400 ul

List Price:

$495.00

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