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Western blot analysis in mouse spleen tissue lysates (35ug/lane).
ERCC8 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in mouse spleen tissue lysates (35ug/lane).

ERCC8 Antibody

CATALOG NUMBER: 55-526

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This ERCC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human ERCC8.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ERCC8
Additional Names:
DNA excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA, ERCC8, CKN1, CSA
Protein Accession Number:
Q13216
Protein Gi Number:
3121917
Ncbi Gene Id Number:
1161
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a WD repeat protein, which interactswith Cockayne syndrome type B (CSB) protein and with p44 protein, asubunit of the RNA polymerase II transcription factor IIH.Mutations in this gene have been identified in patients withhereditary disease Cockayne syndrome (CS). CS cells are abnormallysensitive to ultraviolet radiation and are defective in the repairof transcriptionally active genes.
Background Reference 1:
Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
Background Reference 2:
Guillem, V.M., et al. Am. J. Hematol. 85(7):482-486(2010)
Background Reference 3:
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 4:
Kamenisch, Y., et al. J. Exp. Med. 207(2):379-390(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-526

List Size:
400 ul

List Price:

$495.00

Datasheet
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