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Western blot analysis in 293,HepG2 cell line lysates (35ug/lane).
ERV3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in 293,HepG2 cell line lysates (35ug/lane).

ERV3 Antibody

CATALOG NUMBER: 57-042

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ERV3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human ERV3.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
68 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ERV3-1
Additional Names:
Endogenous retrovirus group 3 member 1 Env polyprotein, ERV-3 envelope protein, ERV3 envelope protein, ERV3-1 envelope protein, Envelope polyprotein, HERV-R envelope protein, ERV-R envelope protein, HERV-R_7q212 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERV3-1, ERV3
Protein Accession Number:
Q14264
Protein Gi Number:
44887883
Ncbi Gene Id Number:
2086
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The human genome includes many retroelements including thehuman endogenous retroviruses (HERVs). ERV3, one of the moststudied HERVs, is thought to have integrated 30 to 40 million yearsago and is present in higher primates with the exception ofgorillas. Taken together, the observation of genome conservation,the detection of transcript expression, and the presence ofconserved ORFs is circumstantial evidence for a functional role. Afunctional role is also suggested by the observation thatdownregulation of ERV3 is reported in choriocarcinoma. [provided byRefSeq].
Background Reference 1:
Andersson, A.C., et al. J. Virol. 79(14):9270-9284(2005)
Background Reference 2:
Herve, C.A., et al. Genomics 83(5):940-943(2004)
Background Reference 3:
Blaise, S., et al. Proc. Natl. Acad. Sci. U.S.A. 100(22):13013-13018(2003)
Background Reference 4:
de Parseval, N., et al. J. Virol. 77(19):10414-10422(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-042

List Size:
400 ul

List Price:

$495.00

Datasheet
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