Estrogen Receptor-alpha (phospho Tyr537) Antibody

CATALOG NUMBER: 79-786

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
Estrogen Receptor-alpha (phospho Tyr537) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 537 (P-L-Y (p)-D-L) derived from Human Estrogen Receptor-alpha.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of ER-alpha only when phosphorylated at tyrosine 537.
Predicted Molecular Weight:
66 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ESR1
Additional Names:
ER, ESR, ESR1, ESTR, NR3A1
Protein Accession Number:
NP_000116.2
Protein Gi Number:
62821794
Ncbi Gene Id Number:
2099
Background:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Background Reference 1:
Sehime Temel, Endocrinology, Oct 2002; 143: 3974.
Background Reference 2:
Xin-Tian Zhang, AACR Meeting Abstracts, Apr 2005; 2005: 302.
Background Reference 3:
Suwit J. Somponpun, Am J Physiol Regulatory Integrative Comp Physiol, Sep 2004; 287: R661 - R669.
Background Reference 4:
Marcello Maggiolini, Cancer Res., Oct 1999;

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-786

List Size:
0.1 mg

List Price:

$376.00

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