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Western blot analysis of extracts from HeLa cells treated with Serum using Phospho-ETK (Tyr566) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HeLa cells treated with Serum using Phospho-ETK (Tyr566) Antibody. The lane on the right is treated with the antigen-specific peptide.

ETK (phospho Tyr566) Antibody

CATALOG NUMBER: 80-003

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
ETK (phospho Tyr566) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine566 (D-Q-Y (p)-V-S) derived from Human ETK.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of ETK only when phosphorylated at tyrosine 566.
Predicted Molecular Weight:
78 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
BMX
Additional Names:
BMX, BMX NON-receptor tyrosine kinase, Bone marrow kinase BMX, Epithelial and endothelial tyrosine kinase, NTK38
Protein Accession Number:
NP_001712.1
Protein Gi Number:
1705489
Ncbi Gene Id Number:
660
Background:
Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility.
Background Reference 1:
Zhang R, et al. (2003) J Biol Chem 278, 51267-76
Background Reference 2:
Tsai YT, et al. (2000) Mol Cell Biol 20, 2043-54

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

80-003

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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