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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

EXOSC1 Antibody

CATALOG NUMBER: 59-892

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This EXOSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the C-terminal region of human EXOSC1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
21 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
EXOSC1
Additional Names:
Exosome complex component CSL4, Exosome component 1, EXOSC1, CSL4
Protein Accession Number:
Q9Y3B2
Protein Gi Number:
14285410
Ncbi Gene Id Number:
51013
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a core component of the exosome. Themammalian exosome is required for rapid degradation of AU richelement-containing RNAs but not for poly(A) shortening. Theassociation of this protein with the exosome is mediated byprotein-protein interactions with ribosomal RNA-processing protein42 and ribosomal RNA-processing protein 46.
Background Reference 1:
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Background Reference 2:
Lehner, B., et al. Genome Res. 14(7):1315-1323(2004)
Background Reference 3:
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Background Reference 4:
Raijmakers, R., et al. J. Mol. Biol. 323(4):653-663(2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-892

List Size:
400 ul

List Price:

$495.00

Datasheet
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