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Western blot analysis in U251 cell line lysates (35ug/lane).
Western blot analysis in U251 cell line lysates (35ug/lane).

EXOSC4 Antibody

CATALOG NUMBER: 59-063

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This EXOSC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids from the Central region of human EXOSC4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
EXOSC4
Additional Names:
Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A, EXOSC4, RRP41, SKI6
Protein Accession Number:
Q9NPD3
Protein Gi Number:
14285756
Ncbi Gene Id Number:
54512
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. Plays a role in replication-dependent histone mRNA degradation.
Background Reference 1:
Mullen, T.E., et al. Genes Dev. 22(1):50-65(2008)
Background Reference 2:
van Dijk, E.L., et al. RNA 13(7):1027-1035(2007)
Background Reference 3:
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Background Reference 4:
Andersen, J.S., et al. Nature 433(7021):77-83(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-063

List Size:
400 ul

List Price:

$495.00

Datasheet
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