F7 Antibody

CATALOG NUMBER: 61-240

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This F7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 302-332 amino acids from human F7.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
52 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
F7
Additional Names:
Coagulation factor VII, 3.4.21.21, Proconvertin, Serum prothrombin conversion accelerator, SPCA, Eptacog alfa, Factor VII light chain, Factor VII heavy chain, F7
Protein Accession Number:
P08709
Protein Gi Number:
119766
Ncbi Gene Id Number:
2155
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
Background Reference 1:
Hagen F.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:2412-2416(1986).
Background Reference 2:
O'Hara P.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:5158-5162(1987).
Background Reference 3:
Sabater-Lleal M.,et al.Hum. Genet. 118:741-751(2006).
Background Reference 4:
Soria J.M.,et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-240

List Size:
200 ul

List Price:

$495.00

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