FADS3 Antibody

CATALOG NUMBER: 59-763

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This FADS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-355 amino acids from the C-terminal region of human FADS3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
51 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FADS3
Additional Names:
Fatty acid desaturase 3, 11419-, Cytochrome b5-related protein, FADS3, CYB5RP
Protein Accession Number:
Q9Y5Q0
Protein Gi Number:
74762790
Ncbi Gene Id Number:
3995
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the fattyacid desaturase (FADS) gene family. Desaturase enzymes regulateunsaturation of fatty acids through the introduction of doublebonds between defined carbons of the fatty acyl chain. FADS familymembers are considered fusion products composed of an N-terminalcytochrome b5-like domain and a C-terminal multiplemembrane-spanning desaturase portion, both of which arecharacterized by conserved histidine motifs. This gene is clusteredwith family members FADS1 and FADS2 at 11q12-q13.1; this cluster isthought to have arisen evolutionarily from gene duplication basedon its similar exon/intron organization.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Mathias, R.A., et al. J. Lipid Res. 51(9):2766-2774(2010)
Background Reference 3:
Barber, M.J., et al. PLoS ONE(3), E9763 (2010) :
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-763

List Size:
400 ul

List Price:

$495.00

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