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FasL Soluble Recombinant Protein

CATALOG NUMBER: 90-312

Specifications
source-species:
HEK293 cells
Species:
Human, Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1.
Fusion Tag:
Fc Tag
Application Note:
This recombinant proteins is for research use only.
Biological Activity:
Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
physical-state:
Lyophilized
Buffer:
Contains PBS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Storage Conditions:
Stable for at least 6 months after receipt when stored at -20°C.
Ncbi Official Symbol:
FASLG
Additional Names:
APO-1L, CD95L, CD178, TNFSF6, Fas Ligand
Protein Accession Number:
P48023
Protein Gi Number:
4557329
Ncbi Gene Id Number:
356
Background:
Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-312

List Size:
10 ug

List Price:

$473.00

Datasheet
Shipping Info

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