FASTK Antibody

CATALOG NUMBER: 56-444

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FASTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human FASTK.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
61 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FASTK
Additional Names:
Fas-activated serine/threonine kinase, FAST kinase, FASTK
Protein Accession Number:
Q14296
Protein Gi Number:
13124202
Ncbi Gene Id Number:
10922
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of theserine/threonine protein kinase family. This kinase was shown to beactivated rapidly during Fas-mediated apoptosis in Jurkat cells. Inresponse to Fas receptor ligation, it phosphorylates TIA1, anapoptosis-promoting nuclear RNA-binding protein. The encodedprotein is a strong inducer of lymphocyte apoptosis. Two transcriptvariants encoding different isoforms have been found for this gene.Other variants exist, but their full-length natures have not yetbeen determined.
Background Reference 1:
Simarro, M., et al. J. Immunol. 184(9):5325-5332(2010)
Background Reference 2:
de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Background Reference 3:
Simarro, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(27):11370-11375(2007)
Background Reference 4:
Wu, C., et al. Proteomics 7(11):1775-1785(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-444

List Size:
400 ul

List Price:

$495.00

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