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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

FBLN5 Antibody

CATALOG NUMBER: 59-590

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FBLN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-421 amino acids from the C-terminal region of human FBLN5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
50 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FBLN5
Additional Names:
Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50, FBLN5, DANCE
Protein Accession Number:
Q9UBX5
Protein Gi Number:
12643876
Ncbi Gene Id Number:
10516
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a secreted,extracellular matrix protein containing an Arg-Gly-Asp (RGD) motifand calcium-binding EGF-like domains. It promotes adhesion ofendothelial cells through interaction of integrins and the RGDmotif. It is prominently expressed in developing arteries but lessso in adult vessels. However, its expression is reinduced inballoon-injured vessels and atherosclerotic lesions, notably inintimal vascular smooth muscle cells and endothelial cells.Therefore, the protein encoded by this gene may play a role invascular development and remodeling. Defects in this gene are acause of autosomal dominant cutis laxa, autosomal recessive cutislaxa type I (CL type I), and age-related macular degeneration type3 (ARMD3).
Background Reference 1:
Schneider, R., et al. J. Mol. Biol. 401(4):605-617(2010)
Background Reference 2:
Zhou, S., et al. Biochem. Biophys. Res. Commun. 398(2):247-253(2010)
Background Reference 3:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 4:
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-590

List Size:
400 ul

List Price:

$495.00

Datasheet
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