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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
Western blot analysis in mouse bladder tissue lysates (35ug/lane).

FBXO8 Antibody

CATALOG NUMBER: 60-087

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This FBXO8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human FBXO8.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FBXO8
Additional Names:
F-box only protein 8, F-box/SEC7 protein FBS, FBXO8, FBS, FBX8
Protein Accession Number:
Q9NRD0
Protein Gi Number:
13124142
Ncbi Gene Id Number:
26269
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofthe ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependentubiquitination. The F-box proteins are divided into 3 classes: Fbwscontaining WD-40 domains, Fbls containing leucine-rich repeats, andFbxs containing either different protein-protein interactionmodules or no recognizable motifs. The protein encoded by this genebelongs to the Fbxs class. It contains a C-terminal amino acidsequence that bears a significant similarity with a portion ofyeast Sec7p, a critical regulator of vesicular protein transport.This human protein may interact with ADP-ribosylationfactor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchangefactor) activity.
Background Reference 1:
Cronin, S., et al. Eur. J. Hum. Genet. 17(2):213-218(2009)
Background Reference 2:
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Background Reference 3:
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Background Reference 4:
Ilyin, G.P., et al. Genomics 67(1):40-47(2000)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-087

List Size:
400 ul

List Price:

$495.00

Datasheet
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