FCAR Antibody

CATALOG NUMBER: 56-731

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human FCAR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
32 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FCAR
Additional Names:
Immunoglobulin alpha Fc receptor, IgA Fc receptor, CD89, FCAR, CD89
Protein Accession Number:
P24071
Protein Gi Number:
119860
Ncbi Gene Id Number:
2204
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the immunoglobulin genesuperfamily and encodes a receptor for the Fc region of IgA. Thereceptor is a transmembrane glycoprotein present on the surface ofmyeloid lineage cells such as neutrophils, monocytes, macrophages,and eosinophils, where it mediates immunologic responses topathogens. It interacts with IgA-opsonized targets and triggersseveral immunologic defense processes, including phagocytosis,antibody-dependent cell-mediated cytotoxicity, and stimulation ofthe release of inflammatory mediators. Multiple alternativelyspliced transcript variants encoding different isoforms have beendescribed for this gene.
Background Reference 1:
Vuong, M.T., et al. Kidney Int. (2010) In press :
Background Reference 2:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 3:
Peng, M., et al. Cell Res. 20(2):223-237(2010)
Background Reference 4:
Kobayashi, T., et al. J. Dent. Res. 88(12):1137-1141(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-731

List Size:
400 ul

List Price:

$495.00

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