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Western blot analysis in HL-60 cell line lysates (35ug/lane).
Western blot analysis in HL-60 cell line lysates (35ug/lane).

FCGR2B Antibody

CATALOG NUMBER: 57-401

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FCGR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the C-terminal region of human FCGR2B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
34 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FCGR2B
Additional Names:
Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD32, FCGR2B, CD32, FCG2, IGFR2
Protein Accession Number:
P31994
Protein Gi Number:
8039788
Ncbi Gene Id Number:
2213
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a low affinityreceptor for the Fc region of immunoglobulin gamma complexes. Theencoded protein is involved in the phagocytosis of immune complexesand in the regulation of antibody production by B-cells. Variationsin this gene may increase susceptibilty to systemic lupuserythematosus (SLE). Several transcript variants encoding differentisoforms have been found for this gene.
Background Reference 1:
Prokopec, K.E., et al. Clin. Immunol. 137(3):322-329(2010)
Background Reference 2:
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Background Reference 3:
Zhang, C.Y., et al. J. Biol. Chem. 285(44):34250-34258(2010)
Background Reference 4:
Niederer, H.A., et al. Hum. Mol. Genet. 19(16):3282-3294(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-401

List Size:
400 ul

List Price:

$495.00

Datasheet
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