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Western blot analysis of lysate from HL-60 cell line, using FCGR3B Antibody at 1:1000.
Western blot analysis of lysate from HL-60 cell line, using FCGR3B Antibody at 1:1000.

FCGR3B Antibody

CATALOG NUMBER: 61-053

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FCGR3B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-47 amino acids from the N-terminal region of human FCGR3B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FCGR3B
Additional Names:
Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb, FcR-10, IgG Fc receptor III-1, CD16b, FCGR3B, CD16B, FCG3, FCGR3, IGFR3
Protein Accession Number:
O75015
Ncbi Gene Id Number:
2215
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Background Reference 1:
Ravetch J.V.,et al.J. Exp. Med. 170:481-497(1989).
Background Reference 2:
Simmons D.,et al.Nature 333:568-570(1988).
Background Reference 3:
Simmons D.,et al.Nature 340:662-662(1989).
Background Reference 4:
Peltz G.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:1013-1017(1989).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-053

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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