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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

FCN1 Antibody

CATALOG NUMBER: 58-889

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human FCN1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
35 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FCN1
Additional Names:
Ficolin-1, Collagen/fibrinogen domain-containing protein 1, Ficolin-A, Ficolin-alpha, M-ficolin, FCN1, FCNM
Protein Accession Number:
O00602
Ncbi Gene Id Number:
2219
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The ficolin family of proteins are characterized by thepresence of a leader peptide, a short N-terminal segment, followedby a collagen-like region, and a C-terminal fibrinogen-like domain.The collagen-like and the fibrinogen-like domains are also foundseparately in other proteins such as complement protein C1q, C-typelectins known as collectins, and tenascins. However, all theseproteins recognize different targets, and are functionallydistinct. Ficolin 1 encoded by FCN1 is predominantly expressed inthe peripheral blood leukocytes, and has been postulated tofunction as a plasma protein with elastin-binding activity.
Background Reference 1:
Honore, C., et al. J. Leukoc. Biol. 88(1):145-158(2010)
Background Reference 2:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 3:
Gout, E., et al. J. Biol. Chem. 285(9):6612-6622(2010)
Background Reference 4:
Wittenborn, T., et al.Innate Immun 2(2):167-180(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-889

List Size:
400 ul

List Price:

$495.00

Datasheet
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