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The purity of rh FetuinA / FETUA / AHSG was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of rh FetuinA / FETUA / AHSG was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

Fetuin A Recombinant Protein

CATALOG NUMBER: 96-311

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Ala 19 - Val 367
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
38.2 kDa
Purity:
>98% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
AHSG
Additional Names:
AHSG, FETUA, Fetuin A
Protein Accession Number:
NP_001613
Ncbi Gene Id Number:
197
Background:
Alpha-2-HS-glycoprotein (AHSG) is also known as Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A (FETUA), is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the cystatin family of proteases inhibitors and the fetuin class of plasma binding proteins. AHSG / Fetuin A is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuins are carrier proteins like albumin. Fetuin-A / AHSG forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus AHSG / Fetuin A is a potent inhibitor of pathological calcification. Fetuin A / FETUA promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Mice deficient in Fetuin-A show systemic calcification of soft tissues.
Background Reference 1:
Jahnen-Dechent W., et al., 1994, Eur. J. Biochem. 226 : 59–69.
Background Reference 2:
Lee C., et al., 2009, Frontiers in Bioscience 14: 2911–2922.
Background Reference 3:
Heiss A., et al., 2008, J. Biol. Chem. 283 (21): 14815–25.
Background Reference 4:
Jahnen-Dechent W., et al., 2008, J. Mol. Med. 86 (4): 379–89.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-311

List Size:
0.1 mg

List Price:

$463.00

Datasheet
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