FGD3 Antibody

CATALOG NUMBER: 60-372

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FGD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-601 amino acids from the C-terminal region of human FGD3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
79 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FGD3
Additional Names:
FYVE, RhoGEF and PH domain-containing protein 3, Zinc finger FYVE domain-containing protein 5, FGD3, ZFYVE5
Protein Accession Number:
Q5JSP0
Protein Gi Number:
61213216
Ncbi Gene Id Number:
89846
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FGD3 promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Delague, V., et al. Am. J. Hum. Genet. 81(1):1-16(2007)
Background Reference 3:
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Background Reference 4:
Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-372

List Size:
400 ul

List Price:

$495.00

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