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FGF-19 Antibody [FG369-1]

CATALOG NUMBER: 36-067

Clonality:
Monoclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Immunogen:
Recombinant human FGF-19.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
ELISA: (direct or indirect: 1:2,000-1:5,000), Immunohistochemistry: (paraffin sections, 15ug/ml). Western blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Specificity:
Recognizes human FGF-19. Detects a band of ~25kDa by Western blot.
Clonality:
Monoclonal
Isotype:
IgG1, kappa
Physical State:
Liquid
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
FGF19
Additional Names:
Fibroblast Growth Factor 19
Protein Accession Number:
11132196
Protein Gi Number:
O95750
Ncbi Gene Id Number:
9965
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-067

List Size:
100 ug

List Price:

$408.00

Datasheet
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