FGF-21 Recombinant Protein

CATALOG NUMBER: 90-101

Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Human FGF-21 (aa 1-209) is fused at the C-terminus to the Fc portion of human IgG1.
Fusion Tag:
Fc Tag
Application Note:
This recombinant proteins is for research use only.
Biological Activity:
Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells.
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
physical-state:
Liquid
Buffer:
0.2um-filtered solution in PBS.
Concentration:
~1mg/ml
Storage Conditions:
Working aliquots are stable for up to 3 months when stored at -20°C.
Ncbi Official Symbol:
FGF21
Additional Names:
Fibroblast Growth Factor 21
Protein Accession Number:
Q9NSA1
Protein Gi Number:
9506597
Ncbi Gene Id Number:
26291
Background:
FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-101

List Size:
50 ug

List Price:

$577.00

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